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These findings illuminate MYT1L’s role in orchestrating gene expression during neuronal development, providing insights into the molecular underpinnings of MYT1L syndrome. Yen, A., Sarafinovska, S., Chen, X. et al. MYT1L deficiency impairs excitatory neuron trajectory during cortical development. Nat Commun 15, 10308 (2024).

Single cell-omics has transformed our understanding of cellular heterogeneity and cell function.

Current protein profiling methods are limited, offering either high parameter analysis or high-throughput capability, but rarely both simultaneously.

Although plate-based fixation-compatible workflows have increased accessibility of single-cell
profiling these workflows can still be challenging to use with complex samples.