MYT1L deficiency impairs excitatory neuron trajectory during cortical development
Every brain cell shares the same genetic code, yet they exhibit a wide range of functions.
Read MoreThe single cell transcriptional landscape of mammalian organogenesis
Most studies of mammalian organogenesis rely on model organisms, and, in particular, the mouse.
Read MoreHigh-throughput robust single cell DNA methylation profiling with sciMETv2
DNA methylation is a key epigenetic property that drives gene regulatory programs in development and disease.
Read MoreMassively multiplex chemical transcriptomics at single cell resolution
High-throughput screens (HTS) are a cornerstone of the pharmaceutical drug discovery pipeline (1, 2)
Read MoreComprehensive single cell transcriptional profiling of a multicellular organism
To resolve cellular heterogeneity, we developed a combinatorial indexing strategy to profile the transcriptomes of single cells or nuclei.
Read MoreHigh-content single cell combinatorial indexing
Single-cell genomics assays have emerged as a dominant platform for interrogating complex biological systems.
Read MoreUltra-high throughput single cell analysis of proteins and RNAs by split-pool synthesis
Single-cell omics provide insight into cellular heterogeneity and function.
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